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Tbio
COLGALT2
Procollagen galactosyltransferase 2

Protein Summary
Description
Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361927
  • ENSP00000354960
  • ENSG00000198756

Symbol
  • C1orf17
  • GLT25D2
  • KIAA0584
  • C1orf17
  • GLT25D2
  • ColGalT 2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.99
PubMedID
0.64
transcription factor binding site profile
0.62
histone modification site profile
0.5
disease
0.49


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.99   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 144   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.99   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 144   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
6
4
7
5.3
96.5
BMI-adjusted hip circumference
3
9
9
93
reticulocyte count
6
4
6
90
BMI-adjusted waist circumference
7
8
17
88.8
reticulocyte measurement
3
2
3
82.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
7
5.3
96.5
BMI-adjusted hip circumference
9
93
reticulocyte count
6
90
BMI-adjusted waist circumference
17
88.8
reticulocyte measurement
3
82.9
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
collagen beta(1-O)galactosyltransferase 2
VGNC:1222
469611
Macaque
collagen beta(1-O)galactosyltransferase 2
717508
Mouse
MGI:2138232
269132
Rat
RGD:1304702
289081
Dog
collagen beta(1-O)galactosyltransferase 2
VGNC:53337
608413
Species
Name
OMA
EggNOG
Inparanoid
Chimp
collagen beta(1-O)galactosyltransferase 2
Macaque
collagen beta(1-O)galactosyltransferase 2
Mouse
Rat
Dog
collagen beta(1-O)galactosyltransferase 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IYK4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Collagen biosynthesis and modifying enzymes (R-HSA-1650814)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Collagen biosynthesis and modifying enzymes
Reactome
Collagen formation
Reactome
Extracellular matrix organization
Name
Explore in Pharos
Explore in Source
Collagen biosynthesis and modifying enzymes
Collagen formation
Extracellular matrix organization
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (107)
1 – 10 of 107
VPS33B
Tbio
Novelty:  0.02221093
p_int:  0.99999892
p_ni:  0.000001076
p_wrong:  4e-9
Data Source:  BioPlex
VIPAS39
Tbio
Novelty:  0.02348642
p_int:  0.999995683
p_ni:  0.0000043
p_wrong:  1.7e-8
Score:  0.177
Data Source:  BioPlex,STRINGDB
COL4A1
Tbio
Novelty:  0.00358049
p_int:  0.999984194
p_ni:  0.000015805
p_wrong:  2e-9
Score:  0.916
Data Source:  BioPlex,STRINGDB
COL2A1
Tbio
Novelty:  0.0011102
p_int:  0.999953598
p_ni:  0.000046384
p_wrong:  1.7e-8
Score:  0.952
Data Source:  BioPlex,STRINGDB
SPATA20
Tdark
Novelty:  0.34126403
p_int:  0.999871944
p_ni:  0.000128056
Data Source:  BioPlex
COL4A2
Tbio
Novelty:  0.00782053
p_int:  0.999863767
p_ni:  0.000136233
Score:  0.956
Data Source:  BioPlex,STRINGDB
COL1A1
Tbio
Novelty:  0.00063584
p_int:  0.999676823
p_ni:  0.000323177
Score:  0.913
Data Source:  BioPlex,STRINGDB
COLQ
Tbio
Family:  Enzyme
Novelty:  0.01414634
p_int:  0.999294694
p_ni:  0.000705306
Data Source:  BioPlex
VWA1
Tbio
Novelty:  0.00212445
p_int:  0.999246829
p_ni:  0.000753102
p_wrong:  6.9e-8
Data Source:  BioPlex
DOK1
Tbio
Novelty:  0.01976327
p_int:  0.99806142
p_ni:  6.1e-8
p_wrong:  0.001938519
Score:  0.187
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  8.99

PubMed score by year
PubTator Score  1.61

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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