Tbio PIANP PILR alpha-associated neural protein

Protein Summary

Description

Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Sep 2011]

Uniprot Accession IDs

• Q8IYJ0
• A8K0T3
• B3KPF7
• B3KRI6
• Q6UX35

Gene Name

• PIANP

Ensembl ID

• ENST00000320591
• ENSP00000317818
• ENSG00000139200
• ENST00000534837
• ENSP00000443919
• ENST00000540656
• ENSP00000442157

Symbol

• C12orf53
• PANP
• PANP
• LEDA1
• leda-1
• C12orf53

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.67
kinase perturbation	0.6
tissue sample	0.58
cell type or tissue	0.55
cell line	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.18   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 102   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.18   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 102   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0