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Tdark
ZNF440
Zinc finger protein 440

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304060
  • ENSP00000305373
  • ENSG00000171295
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.75
tissue sample
0.6
cell line
0.59
protein domain
0.58
small molecule perturbation
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.54   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.54   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (7)
1 – 7 of 7
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.925
Data Source: STRINGDB
C19orf44
Tdark
Novelty: 16.35789474
Score: 0.701
Data Source: STRINGDB
MAFIP
Tdark
Novelty: 0.38054968
Score: 0.681
Data Source: STRINGDB
OR6C4
Tdark
Family: oGPCR
Novelty: 5.07120743
Score: 0.669
Data Source: STRINGDB
DUS3L
Tdark
Family: Enzyme
Novelty: 0.24952542
Score: 0.462
Data Source: STRINGDB
SPATA22
Tbio
Novelty: 0.18061361
Score: 0.442
Data Source: STRINGDB
TMPRSS11A
Tbio
Family: Enzyme
Novelty: 0.06142295
Score: 0.406
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.54

PubMed score by year
PubTator Score  1.06

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer