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Tbio
TEX11
Testis-expressed protein 11

Protein Summary
Description
Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers. This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000344304
  • ENSP00000340995
  • ENSG00000120498
  • ENST00000374320
  • ENSP00000363440
  • ENST00000374333
  • ENSP00000363453
  • ENST00000395889
  • ENSP00000379226

Symbol
  • TGC1
  • TSGA3
  • SPGFX2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.55
cellular component
0.53
cell type or tissue
0.51
biological process
0.5
virus perturbation
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.88   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.88   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (70)
SYCP2
Tbio
Novelty:  0.05040533
Score:  0.988
Data Source:  STRINGDB
MSH4
Tbio
Novelty:  0.00838156
Score:  0.811
Data Source:  STRINGDB
MOV10L1
Tbio
Family:  Enzyme
Novelty:  0.09735465
Score:  0.761
Data Source:  STRINGDB
MSH5
Tbio
Novelty:  0.0109825
Score:  0.75
Data Source:  STRINGDB
TAF7L
Tbio
Novelty:  0.08132691
Score:  0.737
Data Source:  STRINGDB
HFM1
Tbio
Family:  Enzyme
Novelty:  0.01556527
Score:  0.736
Data Source:  STRINGDB
RNF212
Tbio
Family:  Enzyme
Novelty:  0.05189831
Score:  0.726
Data Source:  STRINGDB
HORMAD1
Tbio
Novelty:  0.03649777
Score:  0.711
Data Source:  STRINGDB
GTSF1
Tbio
Novelty:  0.13243562
Score:  0.711
Data Source:  STRINGDB
SPO11
Tbio
Novelty:  0.00273994
Score:  0.708
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
78.4
mean corpuscular volume
1
1
1
17.8
1
1
0
1.1
11.6
refractive error measurement
1
1
1
1.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
78.4
mean corpuscular volume
1
17.8
0
1.1
11.6
refractive error measurement
1
1.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
testis expressed 11
VGNC:1517
465690
Macaque
testis expressed 11
697543
Mouse
MGI:1933237
83558
Rat
RGD:1560239
501588
Dog
testis expressed 11
VGNC:47265
607665
Species
Name
OMA
EggNOG
Inparanoid
Chimp
testis expressed 11
Macaque
testis expressed 11
Mouse
Rat
Dog
testis expressed 11
Publication Statistics
PubMed Score 25.88
PubMed score by year
PubTator Score 9.31
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title