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Tbio
TMEM192
Transmembrane protein 192

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306480
  • ENSP00000305069
  • ENSG00000170088
  • ENST00000506087
  • ENSP00000425335
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
kinase perturbation
0.84
transcription factor perturbation
0.8
cellular component
0.77
tissue sample
0.75


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.13   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.13   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
59
mathematical ability
1
1
1
48.5
cognitive function measurement
1
1
1
33.1
intelligence
1
1
0
5.6
17.8
neuroticism measurement
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
59
mathematical ability
1
48.5
cognitive function measurement
1
33.1
intelligence
0
5.6
17.8
neuroticism measurement
1
15.8
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 192
708459
Mouse
MGI:1920317
73067
Rat
Dog
transmembrane protein 192
VGNC:49838
475489
Horse
transmembrane protein 192
VGNC:24239
100068165
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 192
Mouse
Rat
Dog
transmembrane protein 192
Horse
transmembrane protein 192
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IY95-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (46)
1 – 10 of 46
SEMA4A
Tbio
Novelty:  0.01062916
p_int:  0.999339649
p_ni:  0.000660339
p_wrong:  1.2e-8
Data Source:  BioPlex
SYPL2
Tdark
Novelty:  0.03928948
p_int:  0.99931425
p_ni:  0.00068575
Data Source:  BioPlex
SDC2
Tbio
Novelty:  0.00597758
p_int:  0.998868443
p_ni:  0.001131557
Data Source:  BioPlex
GYPA
Tbio
Novelty:  0.00067203
p_int:  0.995918615
p_ni:  0.004081384
Score:  0.183
Data Source:  BioPlex,STRINGDB
TNFRSF10C
Tbio
Novelty:  0.0088942
p_int:  0.989957851
p_ni:  0.010042141
p_wrong:  8e-9
Data Source:  BioPlex
LILRB3
Tbio
Novelty:  0.01370238
p_int:  0.988242015
p_ni:  0.011757743
p_wrong:  2.42e-7
Score:  0.165
Data Source:  BioPlex,STRINGDB
ASPH
Tbio
Family:  Enzyme
Novelty:  0.00291455
p_int:  0.985897414
p_ni:  0.014102583
p_wrong:  2e-9
Data Source:  BioPlex
IL7R
Tbio
Novelty:  0.00107223
p_int:  0.981843281
p_ni:  0.010077168
p_wrong:  0.008079551
Data Source:  BioPlex
EVA1C
Tbio
Novelty:  0.45928677
p_int:  0.978359225
p_ni:  0.021640774
p_wrong:  1e-9
Data Source:  BioPlex
KLRG2
Tdark
Novelty:  1.19446694
p_int:  0.967477377
p_ni:  0.032522623
Data Source:  BioPlex
Publication Statistics
PubMed Score  5.13

PubMed score by year
PubTator Score  1.85

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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