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Tchem
NIM1K
Serine/threonine-protein kinase NIM1

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.82   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 142   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.82   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Active Ligands (1)
1 – 1 of 1
CHEMBL524266
chemical structure image
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
1
1
69.5
body height
1
1
1
25.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
69.5
body height
1
25.6
Protein-Protein Interactions (25)
1 – 10 of 25
WEE1
Tchem
Family: Kinase
Novelty: 0.00162432
Score: 0.751
Data Source: STRINGDB
CCDC152
Tdark
Novelty: 1.07912575
Score: 0.582
Data Source: STRINGDB
TPCN1
Tchem
Family: IC
Novelty: 0.003844
Score: 0.571
Data Source: STRINGDB
ZNF131
Tbio
Family: TF
Novelty: 0.18894578
Score: 0.568
Data Source: STRINGDB
WDR70
Tdark
Novelty: 0.37521871
Score: 0.558
Data Source: STRINGDB
TSKU
Tbio
Novelty: 0.01876348
Score: 0.531
Data Source: STRINGDB
RIMS3
Tbio
Novelty: 0.06922952
Score: 0.52
Data Source: STRINGDB
NUP155
Tbio
Novelty: 0.03884486
Score: 0.48
Data Source: STRINGDB
GPR26
Tbio
Family: GPCR
Novelty: 0.13362837
Score: 0.479
Data Source: STRINGDB
PARP8
Tdark
Family: Enzyme
Novelty: 0.29808738
Score: 0.477
Data Source: STRINGDB
Publication Statistics
PubMed Score  26.82

PubMed score by year
PubTator Score  8

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer