Tdark KBTBD2 Kelch repeat and BTB domain-containing protein 2

Protein Summary

Uniprot Accession IDs

• Q8IY47
• A8K9T7
• Q86Y62
• Q9P239
• Q9UFM7
• Q9Y382

Gene Name

• KBTBD2

Ensembl ID

• ENST00000304056
• ENSP00000302586
• ENSG00000170852

Symbol

• BKLHD1
• KIAA1489
• BKLHD1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
kinase perturbation	0.88
virus perturbation	0.88
disease perturbation	0.79
histone modification site profile	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.85   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.85   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0