Tbio SLC15A3 Solute carrier family 15 member 3

Protein Summary

Description

Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity).

Uniprot Accession IDs

• Q8IY34
• Q9P2X9

Gene Name

• SLC15A3

Ensembl ID

• ENST00000227880
• ENSP00000227880
• ENSG00000110446

Symbol

• OCTP
• PHT2
• PTR3
• OCTP
• PHT2
• PTR3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	1
histone modification site profile	0.7
tissue sample	0.7
cellular component	0.67
tissue	0.63

Protein Classes

PANTHER Classes

Protein / Transporter / Solute Carrier Family 15 Member 3

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc15 Family Of Peptide Transporters / Solute Carrier Family 15 Member 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 74.08   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 97   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 74.08   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0