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Tbio
CMIP
C-Maf-inducing protein

Protein Summary
Description
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor. This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398040
  • ENSP00000381120
  • ENSG00000153815
  • ENST00000537098
  • ENSP00000446100
  • ENST00000539778
  • ENSP00000440401

Symbol
  • KIAA1694
  • TCMIP
  • TCMIP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
transcription factor perturbation
0.91
transcription factor binding site profile
0.84
transcription factor
0.82
disease perturbation
0.79


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 233.5   (req: < 5)
Gene RIFs: 25   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 233.5   (req: >= 5)
Gene RIFs: 25   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0