Tdark PPIL6 Probable inactive peptidyl-prolyl cis-trans isomerase-like 6

Protein Summary

Description

Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.

Uniprot Accession IDs

• Q8IXY8
• A9NIU0
• A9NIU9
• E7EX15
• PPIase

Gene Name

• PPIL6

Ensembl ID

• ENST00000424445
• ENSP00000407731
• ENSG00000185250
• ENST00000440797
• ENSP00000392257
• ENST00000521072
• ENSP00000427929

Symbol

• PPIase
• RSPH12
• bA425D10.6
• dJ919F19.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
tissue sample	0.65
microRNA	0.61
transcription factor binding site profile	0.52
cellular component	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 157   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 157   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0