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Tbio
HOMEZ
Homeobox and leucine zipper protein Homez

Protein Summary
Description
May function as a transcriptional regulator.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357460
  • ENSP00000350049
  • ENSG00000215271
  • ENST00000561013
  • ENSP00000453979

Symbol
  • KIAA1443
  • KIAA1443
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
virus perturbation
0.72
microRNA
0.64
cell type or tissue
0.63
cellular component
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.39   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 134   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.39   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (8)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (9)
1 – 9 of 9
PPP1CA
Tchem
Family: Enzyme
Novelty: 0.00685545
p_int: 0.999998093
p_ni: 0.000001907
Score: 0.394
Data Source: BioPlex,STRINGDB
DEF6
Tbio
Novelty: 0.00711772
p_int: 0.999969263
p_ni: 0.000030729
p_wrong: 8e-9
Score: 0.213
Data Source: BioPlex,STRINGDB
HOXC8
Tbio
Family: TF
Novelty: 0.0131056
Score: 0.814
Data Source: STRINGDB
TULP4
Tbio
Family: TF
Novelty: 0.06879375
Score: 0.694
Data Source: STRINGDB
DET1
Tbio
Novelty: 0.01807423
Score: 0.574
Data Source: STRINGDB
ADNP2
Tdark
Novelty: 0.21978022
Score: 0.554
Data Source: STRINGDB
SLC41A2
Tdark
Family: Transporter
Novelty: 0.22052506
Score: 0.552
Data Source: STRINGDB
PRDM5
Tbio
Family: TF; Epigenetic
Novelty: 0.01560016
Score: 0.506
Data Source: STRINGDB
TBRG1
Tbio
Novelty: 0.03071036
Score: 0.426
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.39

PubMed score by year
PubTator Score  4.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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