Tbio CD302 CD302 antigen

Protein Summary

Description

Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]

Uniprot Accession IDs

• Q8IX05
• A8K5G4
• B4E2T9
• Q15009

Gene Name

• CD302

Ensembl ID

• ENST00000259053
• ENSP00000259053
• ENSG00000241399
• ENST00000429078
• ENSP00000394301

Symbol

• CLEC13A
• DCL1
• KIAA0022
• DCL1
• DCL-1
• BIMLEC
• CLEC13A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
PubMedID	0.8
virus perturbation	0.79
gene perturbation	0.75
histone modification site profile	0.7
kinase perturbation	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.76   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 223   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.76   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 223   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0