Tdark UEVLD Ubiquitin-conjugating enzyme E2 variant 3

Protein Summary

Description

Possible negative regulator of polyubiquitination.

Uniprot Accession IDs

• Q8IX04
• B2RB69
• B4DL43
• F5H6L6
• H7BYD6
• Q6P2F0
• Q96FF5
• Q9NUX7
• UEV-3

Gene Name

• UEVLD

Ensembl ID

• ENST00000300038
• ENSP00000300038
• ENSG00000151116
• ENST00000320750
• ENSP00000323353
• ENST00000379387
• ENSP00000368697
• ENST00000396197
• ENSP00000379500
• ENST00000535484
• ENSP00000441092
• ENST00000541984
• ENSP00000437538
• ENST00000543987
• ENSP00000442974

Symbol

• UEV3
• ATTP
• UEV3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
histone modification site profile	0.84
kinase perturbation	0.66
virus perturbation	0.64
transcription factor perturbation	0.61

Protein Classes

PANTHER Classes

Protein / Ligase / Ubiquitin-protein Ligase / Ubiquitin-conjugating Enzyme E2 Variant 3

DTO Classes

Protein / Enzyme / Ligase / Ubiquitin-protein Ligase / Ubiquitin-conjugating Enzyme E2 Variant 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.42   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 120   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.42   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0