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Tdark
TRIM42
Tripartite motif-containing protein 42

Protein Summary
Description
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000286349
  • ENSP00000286349
  • ENSG00000155890

Symbol
  • T4A1
  • PPP1R40
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
gene perturbation
0.62
cell line
0.5
tissue sample
0.42
protein complex
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (33)
1 – 10 of 33
SDCBP
Tbio
Novelty: 0.0034118
Score: 0.672
Data Source: STRINGDB
ACTL9
Tdark
Novelty: 0.9298893
Score: 0.646
Data Source: STRINGDB
TRIM77
Tdark
Score: 0.638
Data Source: STRINGDB
CAPZA3
Tdark
Novelty: 0.25693073
Score: 0.562
Data Source: STRINGDB
TRIM64
Tdark
Score: 0.559
Data Source: STRINGDB
PLCZ1
Tbio
Family: Enzyme
Novelty: 0.00685085
Score: 0.546
Data Source: STRINGDB
TRAT1
Tbio
Novelty: 0.00064556
Score: 0.538
Data Source: STRINGDB
TRIM60
Tdark
Novelty: 0.78873239
Score: 0.537
Data Source: STRINGDB
TRIM59
Tbio
Novelty: 0.07453416
Score: 0.537
Data Source: STRINGDB
PCDHB9
Tdark
Novelty: 0.57636422
Score: 0.533
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.29

PubMed score by year
PubTator Score  0.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer