CHERP
Calcium homeostasis endoplasmic reticulum protein
Protein Summary
Involved in calcium homeostasis, growth and proliferation.
- ENST00000546361
- ENSP00000439856
- ENSG00000085872
- DAN26
- SCAF6
- SRA1
- DAN16
- SCAF6
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.94 | ||
histone modification site profile | 0.88 | ||
virus perturbation | 0.88 | ||
co-expressed gene | 0.82 | ||
disease perturbation | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.36 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 193 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.36 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 193 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (264)
RBM17
Novelty: 0.04840999
p_int: 0.999984457
p_ni: 0.000015543
Score: 0.99
Data Source: BioPlex,STRINGDB
PLOD1
Family: Enzyme
Novelty: 0.00905345
p_int: 0.999615757
p_ni: 0.000384243
Data Source: BioPlex
PHF5A
Family: Epigenetic
Novelty: 0.02989472
p_int: 0.997223768
p_ni: 0.002776232
Score: 0.914
Data Source: BioPlex,STRINGDB
ZRSR2
Novelty: 0.03449891
p_int: 0.993206269
p_ni: 0.006793731
Score: 0.666
Data Source: BioPlex,STRINGDB
SFSWAP
Novelty: 0.2236256
p_int: 0.992368193
p_ni: 0.007631807
Score: 0.739
Data Source: BioPlex,STRINGDB
SNRPE
Novelty: 0.02033423
p_int: 0.991967995
p_ni: 0.008032005
Score: 0.925
Data Source: BioPlex,STRINGDB
FGFR2
Family: Kinase
Novelty: 0.00066613
p_int: 0.986381193
p_ni: 0.013618806
p_wrong: 1e-9
Score: 0.16
Data Source: BioPlex,STRINGDB
WDFY2
Novelty: 0.01835759
p_int: 0.979858286
p_ni: 0.020141714
Score: 0.243
Data Source: BioPlex,STRINGDB
JMJD6
Family: Enzyme
Novelty: 0.00305479
p_int: 0.979378277
p_ni: 0.020621723
Data Source: BioPlex
Nearest Tclin Targets
Pathways (5)
Reactome (4)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | mRNA Splicing | ||||
Reactome | mRNA Splicing - Major Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
mRNA Splicing | ||||
mRNA Splicing - Major Pathway | ||||
Viral Interactions (0)
Gene Ontology Terms (13)
Functions (2)
Components (5)
Processes (6)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (10)
Items per page:
1 – 5 of 10
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 4 | 4 | 4 | 98.9 | |||||
leukocyte count | 2 | 3 | 3 | 94.6 | |||||
lymphocyte percentage of leukocytes | 2 | 2 | 2 | 89.7 | |||||
1 | 1 | 0 | 1.1 | 76.1 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 72.5 | |||||
Items per page:
1 – 5 of 10
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
lymphocyte count | 4 | 98.9 | |||||
leukocyte count | 3 | 94.6 | |||||
lymphocyte percentage of leukocytes | 2 | 89.7 | |||||
0 | 1.1 | 76.1 | |||||
monocyte percentage of leukocytes | 1 | 72.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | calcium homeostasis endoplasmic reticulum protein | VGNC:2577 | 455812 | |||||
Macaque | calcium homeostasis endoplasmic reticulum protein | 718689 | ||||||
Mouse | MGI:106417 | 27967 | ||||||
Rat | RGD:1305279 | 290614 | ||||||
Dog | calcium homeostasis endoplasmic reticulum protein | VGNC:39210 | 610237 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | calcium homeostasis endoplasmic reticulum protein | |||||
Macaque | calcium homeostasis endoplasmic reticulum protein | |||||
Mouse | ||||||
Rat | ||||||
Dog | calcium homeostasis endoplasmic reticulum protein | |||||
Publication Statistics
PubMed Score 15.36
PubMed score by year
PubTator Score 6.40
PubTator score by year
Related Publications
Text Mined References (13)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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