Tbio CHERP Calcium homeostasis endoplasmic reticulum protein

Protein Summary

Description

Involved in calcium homeostasis, growth and proliferation.

Uniprot Accession IDs

• Q8IWX8
• O00302
• Q4G0Y5
• Q8WU30
• Q99492

Gene Name

• CHERP

Ensembl ID

• ENST00000546361
• ENSP00000439856
• ENSG00000085872

Symbol

• DAN26
• SCAF6
• SRA1
• DAN16
• SCAF6

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.94
histone modification site profile	0.88
virus perturbation	0.88
co-expressed gene	0.82
disease perturbation	0.79

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Calcium Homeostasis Endoplasmic Reticulum Protein

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Calcium Homeostasis Endoplasmic Reticulum Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.5   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 193   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.5   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 193   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0