SCN4B
Sodium channel subunit beta-4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.98 | ||
molecular function | 0.91 | ||
protein domain | 0.73 | ||
histone modification site profile | 0.64 | ||
PubMedID | 0.57 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Cardiac conduction | ||||
Reactome | Developmental Biology | ||||
Reactome | Interaction between L1 and Ankyrins | ||||
Reactome | L1CAM interactions | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Cardiac conduction | ||||
Developmental Biology | ||||
Interaction between L1 and Ankyrins | ||||
L1CAM interactions | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil count | 3 | 3 | 5 | 94.9 | |||||
leukocyte count | 2 | 2 | 3 | 91.1 | |||||
myeloid white cell count | 2 | 1 | 2 | 84.1 | |||||
monocyte count | 2 | 1 | 2 | 69.3 | |||||
granulocyte count | 1 | 1 | 1 | 62.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil count | 5 | 94.9 | |||||
leukocyte count | 3 | 91.1 | |||||
myeloid white cell count | 2 | 84.1 | |||||
monocyte count | 2 | 69.3 | |||||
granulocyte count | 1 | 62.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | sodium voltage-gated channel beta subunit 4 | VGNC:11660 | 742047 | |||||
Mouse | MGI:2687406 | 399548 | ||||||
Rat | RGD:631404 | 315611 | ||||||
Dog | sodium voltage-gated channel beta subunit 4 | VGNC:53439 | 100688178 | |||||
Horse | sodium voltage-gated channel beta subunit 4 | VGNC:22739 | 100071197 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | sodium voltage-gated channel beta subunit 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | sodium voltage-gated channel beta subunit 4 | |||||
Horse | sodium voltage-gated channel beta subunit 4 | |||||
PMID | Year | Title |
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