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Tbio
ZC3H7A
Zinc finger CCCH domain-containing protein 7A

Protein Classes
Protein Summary
Description
May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'-ATA(A/T)-5' motif in the apical loop.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355758
  • ENSP00000347999
  • ENSG00000122299
  • ENST00000396516
  • ENSP00000379773
  • ENST00000575984
  • ENSP00000459477

Symbol
  • ZC3H7
  • ZC3HDC7
  • ZC3H7
  • HSPC055
  • ZC3HDC7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
transcription factor binding site profile
0.92
virus perturbation
0.88
histone modification site profile
0.67
tissue sample
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
2
1
2
74.7
mathematical ability
1
1
1
48.6
neutrophil count
2
1
2
46.8
testosterone measurement
1
1
1
46.2
vitamin D measurement
1
1
1
40.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
2
74.7
mathematical ability
1
48.6
neutrophil count
2
46.8
testosterone measurement
1
46.2
vitamin D measurement
1
40.9
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (6)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (39)
1 – 10 of 39
BIRC7
Tchem
Novelty: 0.00420245
p_int: 0.999906491
p_ni: 0.000056862
p_wrong: 0.000036646
Score: 0.54
Data Source: BioPlex,STRINGDB
CXorf67
Tdark
Novelty: 0.19833947
Score: 0.672
Data Source: STRINGDB
MKRN1
Tbio
Family: Enzyme
Novelty: 0.04485183
Score: 0.632
Data Source: STRINGDB
NUTM2A
Tdark
Novelty: 0.16557531
Score: 0.629
Data Source: STRINGDB
ZC3H15
Tbio
Novelty: 0.15630592
Score: 0.615
Data Source: STRINGDB
ZC3HAV1L
Tdark
Novelty: 1.84562875
Score: 0.597
Data Source: STRINGDB
ZC3H4
Tbio
Novelty: 0.14897433
Score: 0.583
Data Source: STRINGDB
MEAF6
Tbio
Novelty: 0.0914094
Score: 0.579
Data Source: STRINGDB
MBTD1
Tbio
Family: Epigenetic
Novelty: 0.11651052
Score: 0.559
Data Source: STRINGDB
ZC3H12B
Tbio
Family: Enzyme
Novelty: 0.22787194
Score: 0.556
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.56

PubMed score by year
PubTator Score  0.79

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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