ARHGEF19
Rho guanine nucleotide exchange factor 19
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.84 | ||
tissue sample | 0.66 | ||
cell type or tissue | 0.58 | ||
protein domain | 0.58 | ||
cell line | 0.57 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell death signalling via NRAGE, NRIF and NADE | ||||
Reactome | Death Receptor Signalling | ||||
Reactome | G alpha (12/13) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | NRAGE signals death through JNK | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell death signalling via NRAGE, NRIF and NADE | ||||
Death Receptor Signalling | ||||
G alpha (12/13) signalling events | ||||
GPCR downstream signalling | ||||
NRAGE signals death through JNK | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 5 | 12 | 13 | 3.8 | 99.8 | ||||
low density lipoprotein cholesterol measurement | 5 | 3 | 5 | 88.3 | |||||
aspartate aminotransferase measurement | 2 | 2 | 1 | 13.2 | 83.6 | ||||
balding measurement | 1 | 1 | 1 | 67.1 | |||||
serum albumin measurement | 1 | 2 | 2 | 63 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 13 | 3.8 | 99.8 | ||||
low density lipoprotein cholesterol measurement | 5 | 88.3 | |||||
aspartate aminotransferase measurement | 1 | 13.2 | 83.6 | ||||
balding measurement | 1 | 67.1 | |||||
serum albumin measurement | 2 | 63 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Rho guanine nucleotide exchange factor 19 | VGNC:6720 | 469134 | |||||
Mouse | MGI:1925912 | 213649 | ||||||
Dog | Rho guanine nucleotide exchange factor 19 | VGNC:38079 | 100856630 | |||||
Horse | Rho guanine nucleotide exchange factor 19 | VGNC:15487 | 100053592 | |||||
Cow | Rho guanine nucleotide exchange factor 19 | VGNC:26110 | 617280 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Rho guanine nucleotide exchange factor 19 | |||||
Mouse | ||||||
Dog | Rho guanine nucleotide exchange factor 19 | |||||
Horse | Rho guanine nucleotide exchange factor 19 | |||||
Cow | Rho guanine nucleotide exchange factor 19 | |||||
PMID | Year | Title |
---|