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Tdark
GLB1L2
Beta-galactosidase-1-like protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339772
  • ENSP00000344659
  • ENSG00000149328
  • ENST00000535456
  • ENSP00000444628

Symbol
  • MST114
  • MSTP114
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
histone modification site profile
0.73
tissue sample
0.61
kinase perturbation
0.48
tissue
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.46   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.46   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (56)
SPTB
Tbio
Novelty:  0.00467504
p_int:  0.999991686
p_ni:  0.000008311
p_wrong:  4e-9
Score:  0.2
Data Source:  BioPlex,STRINGDB
CHST6
Tbio
Family:  Enzyme
Novelty:  0.01917947
p_int:  0.989633071
p_ni:  0.010366929
Score:  0.218
Data Source:  BioPlex,STRINGDB
ASIC4
Tbio
Family:  IC
Novelty:  0.02912816
p_int:  0.98623198
p_ni:  0.01376802
Data Source:  BioPlex
MPPE1
Tbio
Family:  Enzyme
Novelty:  0.16027847
p_int:  0.981666156
p_ni:  0.018333844
Data Source:  BioPlex
PEX19
Tbio
Novelty:  0.00605342
p_int:  0.981467459
p_ni:  0.018532541
Data Source:  BioPlex
P2RX1
Tchem
Family:  IC
Novelty:  0.00286826
p_int:  0.976250878
p_ni:  0.023749122
Score:  0.213
Data Source:  BioPlex,STRINGDB
NCEH1
Tchem
Family:  Enzyme
Novelty:  0.01528589
p_int:  0.976184679
p_ni:  0.023815321
Data Source:  BioPlex
TCTN2
Tbio
Novelty:  0.11617528
p_int:  0.974235898
p_ni:  0.025764102
Data Source:  BioPlex
FUT1
Tbio
Family:  Enzyme
Novelty:  0.00597206
p_int:  0.969626998
p_ni:  0.030373002
Data Source:  BioPlex
FUT3
Tbio
Family:  Enzyme
Novelty:  0.0059835
p_int:  0.966867607
p_ni:  0.033132393
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
2
1
8.9
89
insomnia measurement
1
1
0
1.1
26.6
N-glycan measurement
1
1
1
21.5
age at first sexual intercourse measurement
1
1
1
15.8
1
1
0
1.1
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
1
8.9
89
insomnia measurement
0
1.1
26.6
N-glycan measurement
1
21.5
age at first sexual intercourse measurement
1
15.8
0
1.1
14.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
galactosidase beta 1 like 2
VGNC:3268
743376
Mouse
MGI:2388283
244757
Rat
RGD:1564436
503194
Opossum
galactosidase beta 1 like 2
100022614
Anole lizard
galactosidase beta 1 like 2
100563628
Species
Name
OMA
EggNOG
Inparanoid
Chimp
galactosidase beta 1 like 2
Mouse
Rat
Opossum
galactosidase beta 1 like 2
Anole lizard
galactosidase beta 1 like 2
Publication Statistics
PubMed Score 1.46
PubMed score by year
PubTator Score 0.73
PubTator score by year
Related Publications
No publications found