MAPKAPK5
MAP kinase-activated protein kinase 5
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
histone modification site profile | 0.9 | ||
transcription factor binding site profile | 0.83 | ||
kinase perturbation | 0.81 | ||
kinase | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cellular Senescence | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Cellular responses to stress | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cellular Senescence | ||||
Cellular responses to external stimuli | ||||
Cellular responses to stress | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 2 | 0 | 1.9 | 93.2 | |||||
alcohol consumption measurement | 2 | 1 | 1 | 2.5 | 88.6 | ||||
2 | 2 | 0 | 1.6 | 88.5 | |||||
drinking behavior | 1 | 1 | 0 | 6.3 | 88.2 | ||||
coffee consumption measurement | 1 | 1 | 1 | 87.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.9 | 93.2 | |||||
alcohol consumption measurement | 1 | 2.5 | 88.6 | ||||
0 | 1.6 | 88.5 | |||||
drinking behavior | 0 | 6.3 | 88.2 | ||||
coffee consumption measurement | 1 | 87.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | mitogen-activated protein kinase-activated protein kinase 5 | 713521 | ||||||
Mouse | MGI:1333110 | 17165 | ||||||
Rat | RGD:1564113 | 498183 | ||||||
Dog | mitogen-activated protein kinase-activated protein kinase 5 | VGNC:43008 | 477480 | |||||
Horse | mitogen-activated protein kinase-activated protein kinase 5 | VGNC:19968 | 100057579 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | mitogen-activated protein kinase-activated protein kinase 5 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase-activated protein kinase 5 | |||||
Horse | mitogen-activated protein kinase-activated protein kinase 5 | |||||
PMID | Year | Title |
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