Tdark NKAIN4 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4

Protein Summary

Description

NKAIN4 is a member of a family of mammalian proteins (see NKAIN1; MIM 612871) with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]

Uniprot Accession IDs

• Q8IVV8
• Q4VXQ6
• Q9BQU8
• Q9BQU9
• Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4

Gene Name

• NKAIN4

Ensembl ID

• ENST00000370316
• ENSP00000359340
• ENSG00000101198

Symbol

• C20orf58
• FAM77A
• FAM77A
• C20orf58
• bA261N11.2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.59
PubMedID	0.58
tissue	0.55
cellular component	0.45
cell type or tissue	0.43

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 114   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0