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Tdark
CABCOCO1
Ciliary-associated calcium-binding coiled-coil protein 1

Protein Summary
Description
Calcium-binding protein. May be involved in the control of sperm flagellar movement.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330194
  • ENSP00000328698
  • ENSG00000183346
  • ENST00000648843
  • ENSP00000496918

Symbol
  • C10orf107
  • C10orf107
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.29   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.29   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
3
3
3
82.8
Agents acting on the renin-angiotensin system use measurement
1
1
1
79.5
blood pressure
1
1
1
70.2
Calcium channel blocker use measurement
1
1
1
69
Diuretic use measurement
1
1
1
66
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
3
82.8
Agents acting on the renin-angiotensin system use measurement
1
79.5
blood pressure
1
70.2
Calcium channel blocker use measurement
1
69
Diuretic use measurement
1
66
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ciliary associated calcium binding coiled-coil 1
VGNC:3817
745687
Macaque
ciliary associated calcium binding coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28678]
Mouse
MGI:1920537
73287
Rat
RGD:1306739
361834
Dog
ciliary associated calcium binding coiled-coil 1
VGNC:49022
489001
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ciliary associated calcium binding coiled-coil 1
Macaque
ciliary associated calcium binding coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28678]
Mouse
Rat
Dog
ciliary associated calcium binding coiled-coil 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IVU9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Protein-Protein Interactions (45)
1 – 10 of 45
IFNA17
Tbio
Novelty:  0.0030696
p_int:  0.999332086
p_ni:  0.000667907
p_wrong:  8e-9
Score:  0.269
Data Source:  BioPlex,STRINGDB
MOB3C
Tdark
Family:  Enzyme
Novelty:  1.77708434
p_int:  0.996567702
p_ni:  0.003409414
p_wrong:  0.000022884
Score:  0.485
Data Source:  BioPlex,STRINGDB
NME2P1
Tdark
Family:  Kinase
p_int:  0.984086569
p_ni:  0.015913428
p_wrong:  4e-9
Data Source:  BioPlex
VSIG8
Tdark
Novelty:  1.16023405
p_int:  0.978319643
p_ni:  0.021680356
p_wrong:  1e-9
Score:  0.158
Data Source:  BioPlex,STRINGDB
PLCD3
Tbio
Family:  Enzyme
Novelty:  0.04749421
Score:  0.705
Data Source:  STRINGDB
ZNF652
Tbio
Family:  TF
Novelty:  0.09423783
Score:  0.67
Data Source:  STRINGDB
LSMEM1
Tdark
Novelty:  15.71612903
Score:  0.622
Data Source:  STRINGDB
QRICH2
Tdark
Novelty:  0.29388805
Score:  0.59
Data Source:  STRINGDB
PLEKHA7
Tbio
Novelty:  0.05239328
Score:  0.589
Data Source:  STRINGDB
ATP2B1
Tbio
Family:  Transporter
Novelty:  0.00706808
Score:  0.57
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.29

PubMed score by year
PubTator Score  2.63

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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