P3H3
Prolyl 3-hydroxylase 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue | 0.87 | ||
molecular function | 0.81 | ||
gene perturbation | 0.73 | ||
cellular component | 0.61 | ||
tissue sample | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen formation | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Collagen biosynthesis and modifying enzymes | ||||
Collagen formation | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 5 | 2 | 9 | 86.1 | |||||
refractive error measurement | 2 | 1 | 1 | 7.8 | 82.4 | ||||
age at onset | 1 | 1 | 0 | 7.8 | 63.4 | ||||
Myopia | 3 | 1 | 0 | 1.3 | 63.4 | ||||
ganglion cell inner plexiform layer thickness measurement | 1 | 1 | 1 | 58.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 9 | 86.1 | |||||
refractive error measurement | 1 | 7.8 | 82.4 | ||||
age at onset | 0 | 7.8 | 63.4 | ||||
Myopia | 0 | 1.3 | 63.4 | ||||
ganglion cell inner plexiform layer thickness measurement | 1 | 58.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:1315208 | 14789 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
PMID | Year | Title |
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