Protein Summary
Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs. This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- ENST00000349880
- ENSP00000309577
- ENSG00000166833
- ENST00000360655
- ENSP00000353871
- ENST00000396085
- ENSP00000379394
- ENST00000396087
- ENSP00000379396
- ENST00000533917
- ENSP00000437316
- HELAD1
- KIAA1419
- POMFIL2
- RAINB1
- STEERIN2
- HELAD1
- RAINB1
- POMFIL2
- UNC53H2
- STEERIN2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 0.99 | ||
molecular function | 0.95 | ||
virus perturbation | 0.92 | ||
transcription factor perturbation | 0.88 | ||
transcription factor | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 69.88 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 76 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 69.88 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 76 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 12
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0