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Tdark
HID1
Protein HID1

Protein Summary
Description
May play an important role in the development of cancers in a broad range of tissues.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000425042
  • ENSP00000413520
  • ENSG00000167861

Symbol
  • C17orf28
  • DMC1
  • DMC1
  • HID-1
  • 17orf28
  • C17orf28
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.69
gene perturbation
0.65
tissue sample
0.6
PubMedID
0.59
transcription factor
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.48   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 202   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.48   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 202   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
DENND2C
Tbio
Novelty:  1.37746285
p_int:  0.999999416
p_ni:  5.84e-7
Score:  0.692
Data Source:  BioPlex,STRINGDB
USP7
Tchem
Family:  Enzyme
Novelty:  0.00412878
Score:  0.881
Data Source:  STRINGDB
OTOP2
Tdark
Novelty:  0.40535125
Score:  0.819
Data Source:  STRINGDB
TMEM128
Tdark
Novelty:  5.15874803
Score:  0.774
Data Source:  STRINGDB
PTCRA
Tbio
Novelty:  0.01307489
Score:  0.716
Data Source:  STRINGDB
CDR2L
Tbio
Novelty:  0.09295886
Score:  0.709
Data Source:  STRINGDB
STAP2
Tbio
Novelty:  0.00375696
Score:  0.643
Data Source:  STRINGDB
GPD1L
Tbio
Family:  Enzyme
Novelty:  0.0169606
Score:  0.634
Data Source:  STRINGDB
FADS6
Tdark
Family:  Enzyme
Novelty:  1.07260726
Score:  0.626
Data Source:  STRINGDB
DYM
Tbio
Novelty:  0.02348265
Score:  0.612
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
Find Similar Targets
Items per page:
10
1 – 9 of 9
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
1
1
66.3
ferritin measurement
1
1
1
55.2
lymphocyte percentage of leukocytes
2
2
2
55.2
intraocular pressure measurement
1
1
1
30.2
neutrophil percentage of leukocytes
2
1
2
10
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
66.3
ferritin measurement
1
55.2
lymphocyte percentage of leukocytes
2
55.2
intraocular pressure measurement
1
30.2
neutrophil percentage of leukocytes
2
10
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
HID1 domain containing
VGNC:9709
454871
Macaque
HID1 domain containing
699954
Mouse
MGI:2445087
217310
Rat
RGD:1311422
287822
Dog
HID1 domain containing
VGNC:41685
483305
Species
Name
OMA
EggNOG
Inparanoid
Chimp
HID1 domain containing
Macaque
HID1 domain containing
Mouse
Rat
Dog
HID1 domain containing
Publication Statistics
PubMed Score 2.48
PubMed score by year
PubTator Score 5.79
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title