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Tbio
RELL1
RELT-like protein 1

Protein Summary
Description
Induces activation of MAPK14/p38 cascade, when overexpressed (PubMed:28688764). Induces apoptosis, when overexpressed (PubMed:19969290).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314117
  • ENSP00000313385
  • ENSG00000181826
  • ENST00000454158
  • ENSP00000398778
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
histone modification site profile
0.87
microRNA
0.84
kinase perturbation
0.76
transcription factor binding site profile
0.75


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.33   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.33   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RELT like 1
VGNC:12966
461160
Macaque
RELT like 1
697000
Mouse
MGI:2140767
100532
Rat
RGD:1307468
289635
Dog
RELT like 1
VGNC:45468
479117
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RELT like 1
Macaque
RELT like 1
Mouse
Rat
Dog
RELT like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IUW5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (45)
1 – 10 of 45
OXSR1
Tbio
Family: Kinase
Novelty: 0.11142923
p_int: 0.999999928
p_ni: 7.2e-8
Score: 0.873
Data Source: BioPlex,STRINGDB
STK39
Tbio
Family: Kinase
Novelty: 0.00548476
p_int: 0.999999794
p_ni: 2.06e-7
Score: 0.53
Data Source: BioPlex,STRINGDB
TH
Tclin
Family: Enzyme
Novelty: 0.00025719
p_int: 0.999990475
p_ni: 0.000009336
p_wrong: 1.89e-7
Score: 0.19
Data Source: BioPlex,STRINGDB
SNX18
Tbio
Novelty: 0.10461787
p_int: 0.999808407
p_ni: 0.000191593
Score: 0.189
Data Source: BioPlex,STRINGDB
TCAF2
Tbio
Family: Enzyme
Novelty: 0.37070492
p_int: 0.999735825
p_ni: 0.000264175
Data Source: BioPlex
RABL3
Tbio
Family: Enzyme
Novelty: 0.13941945
p_int: 0.995587731
p_ni: 0.003929654
p_wrong: 0.000482615
Score: 0.241
Data Source: BioPlex,STRINGDB
CTNNA3
Tbio
Novelty: 0.01472452
p_int: 0.992956434
p_ni: 0.000256014
p_wrong: 0.006787552
Score: 0.219
Data Source: BioPlex,STRINGDB
ATP5F1B
Tbio
Family: Enzyme
Novelty: 0.01053177
p_int: 0.956366651
p_ni: 0.043633349
Score: 0.216
Data Source: BioPlex,STRINGDB
MGAT1
Tchem
Family: Enzyme
Novelty: 0.01024931
p_int: 0.946867958
p_ni: 0.053132042
Score: 0.219
Data Source: BioPlex,STRINGDB
KDSR
Tbio
Family: Enzyme
Novelty: 0.0408411
p_int: 0.91195799
p_ni: 0.088042007
p_wrong: 4e-9
Score: 0.193
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  4.33

PubMed score by year
PubTator Score  1.03

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer