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Tbio
TMTC1
Transmembrane and TPR repeat-containing protein 1

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 290.17   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 290.17   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (51)
1 – 10 of 51
GNAL
Tbio
Novelty: 0.0277957
Score: 0.75
Data Source: STRINGDB
EBF4
Tbio
Family: TF
Novelty: 0.11214953
Score: 0.731
Data Source: STRINGDB
EBF2
Tbio
Family: TF
Novelty: 0.00851499
Score: 0.726
Data Source: STRINGDB
EBF1
Tbio
Family: TF
Novelty: 0.00140598
Score: 0.724
Data Source: STRINGDB
GRHPR
Tbio
Family: Enzyme
Novelty: 0.01167728
Score: 0.717
Data Source: STRINGDB
RIC8B
Tbio
Novelty: 0.01643643
Score: 0.668
Data Source: STRINGDB
ADCY2
Tbio
Family: Enzyme
Novelty: 0.01612818
Score: 0.664
Data Source: STRINGDB
MYOC
Tbio
Novelty: 0.0019458
Score: 0.66
Data Source: STRINGDB
RGS2
Tbio
Novelty: 0.00413101
Score: 0.641
Data Source: STRINGDB
HTR3A
Tclin
Family: IC
Novelty: 0.00035394
Score: 0.602
Data Source: STRINGDB
Publication Statistics
PubMed Score  290.17

PubMed score by year
PubTator Score  61.22

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer