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Tbio
CILP2
Cartilage intermediate layer protein 2

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.56   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.56   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (51)
1 – 10 of 51
MATN4
Tbio
Novelty: 0.08666783
p_int: 0.999991892
p_ni: 0.000008086
p_wrong: 2.2e-8
Score: 0.28
Data Source: BioPlex,STRINGDB
DEFA5
Tbio
Novelty: 0.01045537
p_int: 0.999988924
p_ni: 3.53e-7
p_wrong: 0.000010723
Data Source: BioPlex
VWCE
Tbio
Novelty: 0.10129635
p_int: 0.999976045
p_ni: 0.000023925
p_wrong: 2.9e-8
Data Source: BioPlex
DEFA1
Tbio
Novelty: 0.01616437
p_int: 0.992946264
p_ni: 0.006910417
p_wrong: 0.000143319
Data Source: BioPlex
TM6SF2
Tbio
Novelty: 0.01262032
Score: 0.83
Data Source: STRINGDB
PBX4
Tbio
Family: TF
Novelty: 0.10934825
Score: 0.792
Data Source: STRINGDB
LYPLAL1
Tbio
Family: Enzyme
Novelty: 0.05795899
Score: 0.68
Data Source: STRINGDB
TRIB1
Tbio
Family: Kinase
Novelty: 0.01783401
Score: 0.669
Data Source: STRINGDB
GALNT2
Tbio
Family: Enzyme
Novelty: 0.03120869
Score: 0.649
Data Source: STRINGDB
FURIN
Tchem
Family: Enzyme
Novelty: 0.00075734
Score: 0.646
Data Source: STRINGDB
Publication Statistics
PubMed Score  8.56

PubMed score by year
PubTator Score  9.73

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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