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Tbio
HRNR
Hornerin

Protein Summary
Description
Component of the epidermal cornified cell envelopes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368801
  • ENSP00000357791
  • ENSG00000197915

Symbol
  • S100A18
  • FLG3
  • S100A16
  • S100a18
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
1
interacting protein
0.9
protein domain
0.73
microRNA
0.55
tissue sample
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.47   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.47   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
1
1
1
96.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
1
96.5
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3046938
68723
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Protein Structure (0 Structures, 9 AlphaFold Models)
RepresentationColor Scheme

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Protein-Protein Interactions (121)
1 – 10 of 121
S100A7
Tbio
Novelty: 0.00434262
Score: 0.955
Data Source: STRINGDB
CAP1
Tbio
Family: Enzyme
Novelty: 0.0333464
Score: 0.915
Data Source: STRINGDB
MAN2B1
Tchem
Family: Enzyme
Novelty: 0.0051017
Score: 0.91
Data Source: STRINGDB
PADI2
Tchem
Family: Enzyme
Novelty: 0.00500966
Score: 0.909
Data Source: STRINGDB
DPP7
Tchem
Family: Enzyme
Novelty: 0.00644738
Score: 0.907
Data Source: STRINGDB
FABP5
Tchem
Novelty: 0.00570755
Score: 0.906
Data Source: STRINGDB
CTSA
Tchem
Family: Enzyme
Novelty: 0.00170931
Score: 0.904
Data Source: STRINGDB
ARG1
Tchem
Family: Enzyme
Novelty: 0.00063728
Score: 0.903
Data Source: STRINGDB
CTSG
Tchem
Family: Enzyme
Novelty: 0.00102052
Score: 0.903
Data Source: STRINGDB
SERPINB3
Tbio
Novelty: 0.00325244
Score: 0.903
Data Source: STRINGDB
Publication Statistics
PubMed Score  35.47

PubMed score by year
PubTator Score  13.69

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer