Protein Summary
Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
- ENST00000331366
- ENSP00000329748
- ENSG00000139117
- ENST00000538596
- ENSP00000439237
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.83 | ||
histone modification site profile | 0.82 | ||
transcription factor perturbation | 0.74 | ||
phenotype | 0.69 | ||
microRNA | 0.67 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.02 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 134 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.02 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 134 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (35)
TMEM185A
Novelty: 0.0262898
p_int: 0.968222411
p_ni: 0.031777589
Score: 0.187
Data Source: BioPlex,STRINGDB
CSPP1
Novelty: 0.02734691
p_int: 0.800246473
p_ni: 0.199753527
Score: 0.221
Data Source: BioPlex,STRINGDB
SLC25A41
Family: Transporter
Novelty: 1.04918395
p_int: 0.780908625
p_ni: 0.219091375
Score: 0.185
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (1)
Components (2)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations ()
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
chronotype measurement | 2 | 5 | 1 | 1.1 | 95.3 | ||||
smoking status measurement | 1 | 1 | 1 | 49.5 | |||||
heart rate | 1 | 1 | 1 | 30.2 | |||||
alcohol consumption measurement | 1 | 1 | 1 | 1.5 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
chronotype measurement | 1 | 1.1 | 95.3 | ||||
smoking status measurement | 1 | 49.5 | |||||
heart rate | 1 | 30.2 | |||||
alcohol consumption measurement | 1 | 1.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | copine 8 | VGNC:8383 | 465378 | |||||
Macaque | copine 8 | 696586 | ||||||
Mouse | MGI:1914121 | 66871 | ||||||
Rat | RGD:1307939 | 362988 | ||||||
Dog | copine 8 | VGNC:39567 | 477646 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | copine 8 | |||||
Macaque | copine 8 | |||||
Mouse | ||||||
Rat | ||||||
Dog | copine 8 | |||||
Publication Statistics
PubMed Score 8.02
PubMed score by year
PubTator Score 3.58
PubTator score by year
Related Publications
Text Mined References (16)
Items per page:
0 of 0
PMID | Year | Title |
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