You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF573
Zinc finger protein 573

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339503
  • ENSP00000340171
  • ENSG00000189144
  • ENST00000357309
  • ENSP00000349861
  • ENST00000392138
  • ENSP00000375983
  • ENST00000536220
  • ENSP00000440464
  • ENST00000590414
  • ENSP00000465020
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.77
cell type or tissue
0.67
tissue sample
0.62
protein domain
0.58
cell line
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.38   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 24   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.38   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
5
2
7
83.9
glomerular filtration rate
3
2
3
82.7
C-reactive protein measurement
1
1
1
62.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
7
83.9
glomerular filtration rate
3
82.7
C-reactive protein measurement
1
62.1
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 573
719389
Horse
zinc finger protein 573
VGNC:25345
102150878
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 573
Horse
zinc finger protein 573
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q86YE8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (7)
1 – 7 of 7
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.99999825
p_wrong:  0.000001749
Score:  0.934
Data Source:  BioPlex,STRINGDB
MRPL44
Tbio
Family:  Enzyme
Novelty:  0.2345047
Score:  0.468
Data Source:  STRINGDB
ZMAT1
Tdark
Novelty:  0.49557172
Score:  0.44
Data Source:  STRINGDB
PSMA8
Tdark
Family:  Enzyme
Novelty:  0.83041547
Score:  0.417
Data Source:  STRINGDB
GATAD1
Tbio
Family:  TF
Novelty:  0.0924778
Score:  0.414
Data Source:  STRINGDB
ANKRD37
Tdark
Novelty:  0.20756658
Score:  0.404
Data Source:  STRINGDB
PSD4
Tbio
Novelty:  0.0674237
Score:  0.4
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.38

PubMed score by year
PubTator Score  0.4

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer