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Tdark
ZNF761
Zinc finger protein 761

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000432094
  • ENSP00000480218
  • ENSG00000160336
  • ENST00000454407
  • ENSP00000481272

Symbol
  • KIAA2033
  • ZNF468
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
cell line
0.66
gene perturbation
0.62
microRNA
0.6
protein domain
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
1
1
39.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
39.6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q86XN6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (15)
1 – 10 of 15
TRIM44
Tbio
Novelty:  0.00483553
p_int:  0.824930234
p_ni:  4.3e-8
p_wrong:  0.175069723
Score:  0.225
Data Source:  BioPlex,STRINGDB
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.908
Data Source:  STRINGDB
CARD8
Tbio
Family:  Enzyme
Novelty:  0.0146799
Score:  0.476
Data Source:  STRINGDB
CREG2
Tdark
Novelty:  0.83142703
Score:  0.457
Data Source:  STRINGDB
SREK1IP1
Tdark
Novelty:  1.39429464
Score:  0.447
Data Source:  STRINGDB
HTATIP2
Tbio
Family:  Enzyme
Novelty:  0.01940704
Score:  0.446
Data Source:  STRINGDB
ZFYVE16
Tbio
Novelty:  0.10765234
Score:  0.446
Data Source:  STRINGDB
SFXN3
Tbio
Novelty:  0.18698456
Score:  0.44
Data Source:  STRINGDB
ANKRA2
Tbio
Novelty:  0.19358401
Score:  0.436
Data Source:  STRINGDB
RELL1
Tbio
Novelty:  0.28949625
Score:  0.422
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.83

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer