Tbio VSIG1 V-set and immunoglobulin domain-containing protein 1

Protein Summary

Description

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Uniprot Accession IDs

• Q86XK7
• C9J4P2
• Q6MZS4

Gene Name

• VSIG1

Ensembl ID

• ENST00000217957
• ENSP00000217957
• ENSG00000101842
• ENST00000415430
• ENSP00000402219

Symbol

• GPA34
• GPA34
• dJ889N15.1
• 1700062D20Rik

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
microRNA	0.52
gene perturbation	0.44
tissue sample	0.42
tissue	0.41

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.43   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 171   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.43   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 171   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0