Tdark COMTD1 Catechol O-methyltransferase domain-containing protein 1

Protein Summary

Description

Putative O-methyltransferase.

Uniprot Accession IDs

• Q86VU5
• Q8TE79

Gene Name

• COMTD1

Ensembl ID

• ENST00000372538
• ENSP00000361616
• ENSG00000165644

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.86
cell type or tissue	0.78
transcription factor	0.59
disease perturbation	0.56
PubMedID	0.56

Protein Classes

PANTHER Classes

Protein / Transferase / Methyltransferase / Catechol O-methyltransferase Domain-containing Protein 1

DTO Classes

Protein / Enzyme / Transferase / Methyltransferase / Catechol O-methyltransferase Domain-containing Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.16   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 78   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.16   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0