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Tbio
ZNF410
Zinc finger protein 410

Protein Summary
Description
Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324593
  • ENSP00000323293
  • ENSG00000119725
  • ENST00000398139
  • ENSP00000381208
  • ENST00000442160
  • ENSP00000407130
  • ENST00000540593
  • ENSP00000442228
  • ENST00000555044
  • ENSP00000451763
  • ENST00000615736
  • ENSP00000483073

Symbol
  • APA1
  • APA1
  • APA-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
histone modification site profile
0.81
hub protein
0.79
virus perturbation
0.79
disease perturbation
0.68


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.75   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.75   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 410
VGNC:12443
453024
Macaque
zinc finger protein 410
698124
Mouse
MGI:1289280
52708
Rat
RGD:1305636
314310
Dog
zinc finger protein 410
VGNC:48722
490776
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 410
Macaque
zinc finger protein 410
Mouse
Rat
Dog
zinc finger protein 410
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q86VK4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (31)
1 – 10 of 31
TFCP2
Tbio
Family: TF
Novelty: 0.00687548
Score: 0.73
Data Source: STRINGDB
VDR
Tclin
Family: NR
Novelty: 0.00058366
Score: 0.702
Data Source: STRINGDB
CIPC
Tdark
Novelty: 0.02263148
Score: 0.69
Data Source: STRINGDB
ALG9
Tbio
Family: Enzyme
Novelty: 0.02975572
Score: 0.681
Data Source: STRINGDB
VTA1
Tbio
Novelty: 0.01697854
Score: 0.677
Data Source: STRINGDB
ITGB1BP1
Tbio
Novelty: 0.03944856
Score: 0.67
Data Source: STRINGDB
NMBR
Tchem
Family: GPCR
Novelty: 0.01642469
Score: 0.656
Data Source: STRINGDB
ASAP2
Tbio
Novelty: 0.02744569
Score: 0.633
Data Source: STRINGDB
MSRA
Tbio
Family: Enzyme
Novelty: 0.00595154
Score: 0.614
Data Source: STRINGDB
CDX2
Tbio
Family: TF
Novelty: 0.00081636
Score: 0.589
Data Source: STRINGDB
Publication Statistics
PubMed Score  104.75

PubMed score by year
PubTator Score  52.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer