Tbio IQGAP3 Ras GTPase-activating-like protein IQGAP3

Protein Summary

Uniprot Accession IDs

• Q86VI3
• Q5T3H8

Gene Name

• IQGAP3

Ensembl ID

• ENST00000361170
• ENSP00000354451
• ENSG00000183856

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.98
protein domain	0.85
kinase perturbation	0.81
biological process	0.75
disease perturbation	0.74

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / G-protein Modulator / Ras Gtpase-activating-like Protein Iqgap3

DTO Classes

Protein / Enzyme Modulator / G-protein Modulator / Ras Gtpase-activating-like Protein Iqgap3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.29   (req: < 5)

Gene RIFs: 21   (req: <= 3)

Antibodies: 162   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.29   (req: >= 5)

Gene RIFs: 21   (req: > 3)

Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0