Tdark MYPOP Myb-related transcription factor, partner of profilin

Protein Summary

Description

Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'. Dimerization with PFN1 reduces its DNA-binding capacity (By similarity).

Uniprot Accession IDs

• Q86VE0

Gene Name

• MYPOP

Ensembl ID

• ENST00000322217
• ENSP00000325402
• ENSG00000176182

Symbol

• P42POP
• P42pop

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
histone modification site profile	0.78
protein domain	0.58
cell line	0.56
transcription factor	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.4   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 22   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.4   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0