Tbio CABP7 Calcium-binding protein 7

Protein Summary

Description

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.

Uniprot Accession IDs

• Q86V35
• CaBP7

Gene Name

• CABP7

Ensembl ID

• ENST00000216144
• ENSP00000216144
• ENSG00000100314

Symbol

• CALN2
• CALN2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.88
cell line	0.59
protein domain	0.58
transcription factor	0.57
PubMedID	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.34   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 101   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.34   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0