Tbio GGN Gametogenetin

Protein Summary

Description

May be involved in spermatogenesis. This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q86UU5
• Q7RTU6
• Q86UU4
• Q8NAA1

Gene Name

• GGN

Ensembl ID

• ENST00000334928
• ENSP00000334940
• ENSG00000179168
• ENST00000585737
• ENSP00000467295

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.76
histone modification site profile	0.73
tissue	0.65
transcription factor	0.64
cellular component	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.34   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 66   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.34   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0