PDZD3
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.74 | ||
tissue | 0.67 | ||
PubMedID | 0.58 | ||
biological process | 0.54 | ||
cellular component | 0.51 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Infectious disease | ||||
Reactome | Intestinal infectious diseases | ||||
Reactome | Uptake and actions of bacterial toxins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Infectious disease | ||||
Intestinal infectious diseases | ||||
Uptake and actions of bacterial toxins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 5 | 5 | 6 | 6.3 | 98.8 | ||||
platelet crit | 2 | 4 | 5 | 97.4 | |||||
mean reticulocyte volume | 1 | 2 | 2 | 94.6 | |||||
lymphocyte count | 3 | 3 | 3 | 88.2 | |||||
mean corpuscular volume | 1 | 2 | 2 | 81 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 6 | 6.3 | 98.8 | ||||
platelet crit | 5 | 97.4 | |||||
mean reticulocyte volume | 2 | 94.6 | |||||
lymphocyte count | 3 | 88.2 | |||||
mean corpuscular volume | 2 | 81 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | PDZ domain containing 3 | VGNC:1089 | 466803 | |||||
Macaque | PDZ domain containing 3 | 704100 | ||||||
Mouse | MGI:2429554 | 170761 | ||||||
Rat | RGD:1559807 | 500986 | ||||||
Dog | PDZ domain containing 3 | VGNC:44400 | 610585 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | PDZ domain containing 3 | |||||
Macaque | PDZ domain containing 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | PDZ domain containing 3 | |||||
PMID | Year | Title |
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