RPAIN
RPA-interacting protein
Protein Summary
Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.
- ENST00000327154
- ENSP00000315069
- ENSG00000129197
- ENST00000381208
- ENSP00000370605
- ENST00000381209
- ENSP00000370606
- ENST00000405578
- ENSP00000385814
- ENST00000536255
- ENSP00000439939
- ENST00000539417
- ENSP00000446453
- ENST00000571558
- ENSP00000458699
- ENST00000573577
- ENSP00000460162
- ENST00000574003
- ENSP00000467178
- ENST00000575112
- ENSP00000460354
- ENST00000575599
- ENSP00000458218
- RIP
- RIP
- HRIP
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.87 | ||
transcription factor perturbation | 0.74 | ||
transcription factor binding site profile | 0.72 | ||
cellular component | 0.67 | ||
kinase perturbation | 0.66 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 46.2 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 169 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 46.2 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 169 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0