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Tdark
NOP9
Nucleolar protein 9

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000267425
  • ENSP00000267425
  • ENSG00000196943
  • ENST00000396802
  • ENSP00000380020
  • ENST00000642262
  • ENSP00000493692
  • ENSG00000285326
  • ENST00000644840
  • ENSP00000495668

Symbol
  • C14orf21
  • KIAA2021
  • C14orf21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
tissue sample
0.71
protein complex
0.6
ligand (protein) perturbation
0.59
interacting protein
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.79   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.79   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
3.9
27.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
3.9
27.7
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
NOP9 nucleolar protein
VGNC:3362
467411
Macaque
NOP9 nucleolar protein
715969
Mouse
MGI:1915092
67842
Rat
RGD:1308396
290235
Dog
NOP9 nucleolar protein
VGNC:43893
608429
Species
Name
OMA
EggNOG
Inparanoid
Chimp
NOP9 nucleolar protein
Macaque
NOP9 nucleolar protein
Mouse
Rat
Dog
NOP9 nucleolar protein
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (224)
1 – 10 of 224
TMEM206
Tdark
Novelty: 0.17311172
p_int: 0.999948695
p_ni: 0.000051304
p_wrong: 1e-9
Data Source: BioPlex
UXS1
Tbio
Family: Enzyme
Novelty: 0.04671281
p_int: 0.999836478
p_ni: 0.000163521
p_wrong: 1e-9
Data Source: BioPlex
AMIGO1
Tbio
Novelty: 0.00864791
p_int: 0.997679197
p_ni: 0.002320803
Data Source: BioPlex
PTGER3
Tclin
Family: GPCR
Novelty: 0.0012681
p_int: 0.99420512
p_ni: 0.005794752
p_wrong: 1.29e-7
Data Source: BioPlex
EPHA1
Tchem
Family: Kinase
Novelty: 0.00136672
p_int: 0.991601016
p_ni: 0.008398984
Data Source: BioPlex
TMEM9
Tbio
Novelty: 0.06916197
p_int: 0.989402909
p_ni: 0.010597091
Data Source: BioPlex
SIGLECL1
Tdark
p_int: 0.987864292
p_ni: 0.012135701
p_wrong: 7e-9
Data Source: BioPlex
CD70
Tbio
Novelty: 0.00420393
p_int: 0.973633537
p_ni: 0.026366141
p_wrong: 3.22e-7
Data Source: BioPlex
CYB5B
Tbio
Novelty: 0.09395308
p_int: 0.973569216
p_ni: 0.026430784
Data Source: BioPlex
BYSL
Tbio
Novelty: 0.01919968
p_int: 0.965177863
p_ni: 0.034822136
p_wrong: 1e-9
Score: 0.932
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  0.79

PubMed score by year
PubTator Score  2.73

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer