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Tbio
RBM23
Probable RNA-binding protein 23

Protein Summary
Description
Probable RNA-binding protein. May be involved in pre-mRNA splicing process. This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000346528
  • ENSP00000339220
  • ENSG00000100461
  • ENST00000359890
  • ENSP00000352956
  • ENST00000399922
  • ENSP00000382806

Symbol
  • RNPC4
  • PP239
  • RNPC4
  • CAPERbeta
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
tissue sample
0.69
tissue
0.67
cell line
0.63
kinase perturbation
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (9)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (97)
1 – 10 of 97
JMJD6
Tbio
Family: Enzyme
Novelty: 0.00134844
p_int: 0.999998965
p_ni: 0.000001033
p_wrong: 3e-9
Score: 0.16
Data Source: BioPlex,STRINGDB
PRM2
Tbio
Novelty: 0.00641454
p_int: 0.999994662
p_ni: 0.000005338
Data Source: BioPlex
CHCHD10
Tbio
Novelty: 0.01816269
p_int: 0.999810582
p_ni: 0.000189417
Score: 0.193
Data Source: BioPlex,STRINGDB
CLEC3A
Tdark
Novelty: 0.28952784
p_int: 0.999735231
p_ni: 0.000264764
p_wrong: 4e-9
Data Source: BioPlex
CHCHD2
Tbio
Novelty: 0.02070317
p_int: 0.999697781
p_ni: 0.000302216
p_wrong: 3e-9
Data Source: BioPlex
RNASEH1
Tchem
Family: Enzyme
Novelty: 0.04998588
p_int: 0.999323384
p_ni: 0.000676614
p_wrong: 2e-9
Data Source: BioPlex
TNFRSF13B
Tbio
Novelty: 0.00443808
p_int: 0.998608898
p_ni: 0.001391092
p_wrong: 1e-8
Data Source: BioPlex
LUC7L
Tbio
Novelty: 0.08359873
p_int: 0.998172183
p_ni: 0.001827817
Score: 0.407
Data Source: BioPlex,STRINGDB
BHLHA15
Tbio
Family: TF
Novelty: 0.0466079
p_int: 0.998065945
p_ni: 0.001933673
p_wrong: 3.82e-7
Data Source: BioPlex
SCRIB
Tbio
Novelty: 0.01369885
p_int: 0.995464025
p_ni: 0.004535975
Score: 0.178
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  15.54

PubMed score by year
PubTator Score  3.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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