Tchem ADCK1 Uncharacterized aarF domain-containing protein kinase 1

Protein Summary

Description

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Uniprot Accession IDs

• Q86TW2
• B3KUD5
• Q6PD65
• Q9UIE6

Gene Name

• ADCK1

Ensembl ID

• ENST00000238561
• ENSP00000238561
• ENSG00000063761
• ENST00000341211
• ENSP00000339663

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.9
molecular function	0.9
transcription factor binding site profile	0.77
transcription factor	0.66
tissue sample	0.58

Protein Classes

PANTHER Classes

Protein / ... / Serine Protease / Uncharacterized Aarf Domain-containing Protein Kinase 1

DTO Classes

Protein / Kinase / Protein Kinase / Atypical Group / Abc1 Family / Abc1-b Subfamily / Uncharacterized Aarf Domain-containing Protein Kinase 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.04   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 164   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.04   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1