Tbio DDX53 Probable ATP-dependent RNA helicase DDX53

Protein Summary

Description

This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Other members of this protein family participate in ATP-dependent RNA unwinding. [provided by RefSeq, Sep 2011]

Uniprot Accession IDs

• Q86TM3
• Q0D2N2
• Q6NVV4

Gene Name

• DDX53

Ensembl ID

• ENST00000327968
• ENSP00000368667
• ENSG00000184735

Symbol

• CAGE
• CAGE
• CT26

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.97
molecular function	0.93
tissue	0.63
cell type or tissue	0.51
cell line	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1320.65   (req: < 5)

Gene RIFs: 15   (req: <= 3)

Antibodies: 145   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1320.65   (req: >= 5)

Gene RIFs: 15   (req: > 3)

Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0