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Tbio
SDCCAG8
Serologically defined colon cancer antigen 8

Protein Summary
Description
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis. This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366541
  • ENSP00000355499
  • ENSG00000054282
  • ENST00000622598
  • ENSP00000483550
  • ENSG00000276111

Symbol
  • CCCAP
  • NPHP10
  • BBS16
  • CCCAP
  • SLSN7
  • NPHP10
  • hCCCAP
  • HSPC085
  • NY-CO-8
  • CCCAP SLSN7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
transcription factor binding site profile
0.88
transcription factor
0.86
virus perturbation
0.79
phenotype
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.05   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 221   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.05   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 221   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0