Tbio ZAR1 Zygote arrest protein 1

Protein Summary

Description

Essential for female fertility. May play a role in the oocyte-to-embryo transition (By similarity). This maternal effect gene is oocyte-specific and encodes a protein that is thought to function in the initiation of embryogenesis. A similar protein in mouse is required for female fertility. [provided by RefSeq, Jul 2013]

Uniprot Accession IDs

• Q86SH2

Gene Name

• ZAR1

Ensembl ID

• ENST00000327939
• ENSP00000329803
• ENSG00000182223

Symbol

• Z3CXXC6

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.56
kinase perturbation	0.48
PubMedID	0.46
biological term	0.39
cell line	0.37

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.87   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 105   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.87   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0