Protein Summary
May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases.
- ENST00000329256
- ENSP00000329008
- ENSG00000184330
- ENST00000368728
- ENSP00000357717
- ENST00000368729
- ENSP00000357718
- S100A15
- S100A7L1
- NICE2
- NICE-2
- S100A15
- S100A7f
- S100A7L1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.73 | ||
microRNA | 0.6 | ||
protein complex | 0.45 | ||
cell line | 0.42 | ||
transcription factor | 0.42 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.3 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 30 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.3 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 30 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (34)
TBC1D22B
Novelty: 0.49852962
p_int: 0.999992868
p_ni: 3.51e-7
p_wrong: 0.000006782
Data Source: BioPlex
CDK15
Family: Kinase
Novelty: 0.3870338
p_int: 0.999991139
p_ni: 0.000005626
p_wrong: 0.000003235
Data Source: BioPlex
SUSD3
Novelty: 0.43699506
p_int: 0.999973951
p_ni: 0.000026049
p_wrong: 1e-9
Score: 0.211
Data Source: BioPlex,STRINGDB
RASGEF1C
Novelty: 0.93266395
p_int: 0.999844302
p_ni: 0.000090117
p_wrong: 0.000065581
Score: 0.485
Data Source: BioPlex,STRINGDB
FMNL2
Novelty: 0.03453161
p_int: 0.999840045
p_ni: 0.000065306
p_wrong: 0.000094649
Data Source: BioPlex
CCNYL1
Novelty: 0.45350824
p_int: 0.999798662
p_ni: 0.000116941
p_wrong: 0.000084396
Score: 0.183
Data Source: BioPlex,STRINGDB
KLHL11
Novelty: 0.1537041
p_int: 0.999741052
p_ni: 0.000001933
p_wrong: 0.000257014
Data Source: BioPlex
UGT1A10
Family: Enzyme
Novelty: 0.01535804
p_int: 0.998892784
p_ni: 0.000133863
p_wrong: 0.000973354
Score: 0.234
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (4)
Reactome (4)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Antimicrobial peptides | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Metal sequestration by antimicrobial proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Antimicrobial peptides | ||||
Immune System | ||||
Innate Immune System | ||||
Metal sequestration by antimicrobial proteins | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (3)
Components (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil percentage of leukocytes | 1 | 1 | 1 | 38.2 | |||||
monocyte percentage of leukocytes | 2 | 1 | 2 | 34.8 | |||||
monocyte count | 1 | 1 | 1 | 28 | |||||
basophil percentage of leukocytes | 1 | 1 | 1 | 17 | |||||
matrix metalloproteinase 8 measurement | 1 | 1 | 1 | 14.2 | |||||
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil percentage of leukocytes | 1 | 38.2 | |||||
monocyte percentage of leukocytes | 2 | 34.8 | |||||
monocyte count | 1 | 28 | |||||
basophil percentage of leukocytes | 1 | 17 | |||||
matrix metalloproteinase 8 measurement | 1 | 14.2 | |||||
Find similar targets by:
IDG Resources
Orthologs (2)
1 – 2 of 2
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Horse | S100 calcium binding protein A7 | 100033976 | ||||||
Cow | S100 calcium binding protein A7 | 282344 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Horse | S100 calcium binding protein A7 | |||||
Cow | S100 calcium binding protein A7 | |||||
Publication Statistics
PubMed Score 15.30
PubMed score by year
PubTator Score 17.73
PubTator score by year
Related Publications
Text Mined References (14)
GeneRif Annotations (6)
Items per page:
0 of 0
PMID | Year | Title |
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