Protein Summary
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
- ENST00000289820
- ENSP00000289820
- ENSG00000158806
- ENST00000381530
- ENSP00000370941
- ENST00000397940
- ENSP00000381032
- ENST00000518119
- ENSP00000427741
- ENST00000521157
- ENSP00000429413
- ENST00000615914
- ENSP00000481018
- ENST00000621538
- ENSP00000481077
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.83 | ||
histone modification site profile | 0.64 | ||
cellular component | 0.63 | ||
biological process | 0.6 | ||
tissue sample | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.98 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 90 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.98 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 90 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 12
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0