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Tdark
ADGRD2
Adhesion G-protein coupled receptor D2

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334810
  • ENSP00000335156
  • ENSG00000180264

Symbol
  • GPR144
  • PGR24
  • PGR24
  • GPR144
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
cell line
0.52
cell type or tissue
0.51
disease
0.41
tissue
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (14)
1 – 10 of 14
ADGRA1
Tdark
Family: GPCR
Novelty: 0.29901219
Score: 0.705
Data Source: STRINGDB
GPR174
Tchem
Family: GPCR
Novelty: 0.11487394
Score: 0.687
Data Source: STRINGDB
GPR157
Tdark
Family: GPCR
Novelty: 0.9
Score: 0.649
Data Source: STRINGDB
GPR173
Tbio
Family: GPCR
Novelty: 0.16797659
Score: 0.596
Data Source: STRINGDB
GPR176
Tdark
Family: GPCR
Novelty: 0.43322356
Score: 0.596
Data Source: STRINGDB
ADGRA3
Tbio
Family: GPCR
Novelty: 0.10970026
Score: 0.594
Data Source: STRINGDB
PIP5K1A
Tbio
Family: Kinase
Novelty: 0.08213456
Score: 0.538
Data Source: STRINGDB
ZNF800
Tdark
Family: TF
Novelty: 4
Score: 0.511
Data Source: STRINGDB
PIP5K1C
Tchem
Family: Kinase
Novelty: 0.03766555
Score: 0.485
Data Source: STRINGDB
PSMB7
Tbio
Family: Enzyme
Novelty: 0.13674668
Score: 0.485
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.53

PubMed score by year
PubTator Score  0.25

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer